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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DOK2 All Species: 13.03
Human Site: T144 Identified Species: 31.85
UniProt: O60496 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O60496 NP_003965.2 412 45379 T144 E L Y S S A V T V G P H K E F
Chimpanzee Pan troglodytes XP_519640 412 45373 T144 E L Y S S A V T V G P H K E F
Rhesus Macaque Macaca mulatta XP_001114039 206 22378
Dog Lupus familis XP_543259 411 45419 T143 N E L Y S S T T A G L G R S L
Cat Felis silvestris
Mouse Mus musculus O70469 412 45504 T146 N E L Y S S S T T G L C K E Y
Rat Rattus norvegicus Q4QQV2 480 52151 E151 S L Y S P T W E G S Q F W V T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506018 432 47473 T147 K A G S L S P T A L P C K E F
Chicken Gallus gallus A3R064 426 47148 S141 M E E N C L Y S S W Q D L T E
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_998253 575 63920 Y143 M A E N L I Y Y S R E E V N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_792985 602 64705 Y148 E L Q D N L L Y D S C D N K S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 46.5 84.2 N.A. 74.5 34.5 N.A. 64.8 33.7 N.A. 33 N.A. N.A. N.A. N.A. 23.9
Protein Similarity: 100 99.5 47.3 87.8 N.A. 79.3 45.2 N.A. 74 48.1 N.A. 44.7 N.A. N.A. N.A. N.A. 35.8
P-Site Identity: 100 100 0 20 N.A. 33.3 20 N.A. 40 0 N.A. 0 N.A. N.A. N.A. N.A. 13.3
P-Site Similarity: 100 100 0 33.3 N.A. 46.6 20 N.A. 53.3 13.3 N.A. 6.6 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 20 0 0 0 20 0 0 20 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 10 20 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 10 0 0 20 0 0 0 % D
% Glu: 30 30 20 0 0 0 0 10 0 0 10 10 0 40 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 30 % F
% Gly: 0 0 10 0 0 0 0 0 10 40 0 10 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % H
% Ile: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 40 10 0 % K
% Leu: 0 40 20 0 20 20 10 0 0 10 20 0 10 0 10 % L
% Met: 20 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 20 0 0 20 10 0 0 0 0 0 0 0 10 10 0 % N
% Pro: 0 0 0 0 10 0 10 0 0 0 30 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 20 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 10 0 0 10 0 0 % R
% Ser: 10 0 0 40 40 30 10 10 20 20 0 0 0 10 10 % S
% Thr: 0 0 0 0 0 10 10 50 10 0 0 0 0 10 10 % T
% Val: 0 0 0 0 0 0 20 0 20 0 0 0 10 10 0 % V
% Trp: 0 0 0 0 0 0 10 0 0 10 0 0 10 0 0 % W
% Tyr: 0 0 30 20 0 0 20 20 0 0 0 0 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _